Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2896401 | 0.77 | ALDH1A1 (0.66) | MEN1KMT2ASMN1; SMN2GAAMAPK1 | |
| SCHEMBL2895158 | 0.77 | ALDH1A1 (0.61) | MEN1KMT2ASMN1; SMN2GAACYP2C19 | |
| SCHEMBL29451550 | 0.77 | KMT2A (0.51) | MEN1KMT2ASMN1; SMN2GAAMAPK1 | |
| SCHEMBL29451328 | 0.77 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2GAAMAPK1 | |
| SCHEMBL2888331 | 0.74 | SMN1; SMN2 (0.51) | MEN1KMT2ASMN1; SMN2GAAMAPK1 | |
| SCHEMBL10815353 | 0.74 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2GAAMAPK1 | |
| SCHEMBL29452222 | 0.73 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2GAAMAPK1 | |
| SCHEMBL17767138 | 0.72 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2GAAMAPK1 | |
| SCHEMBL29451899 | 0.72 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2GAAMAPK1 | |
| SCHEMBL25381986 | 0.71 | GPR139 (0.56) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009057827-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF AS P2X7 RECEPTOR INHIBITORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-05-07 | — | — | WO | disclosed |