Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 19/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908106 | 0.91 | LTA4H (0.52) | LTA4HEPHX2KCNH2 | |
| SCHEMBL1904711 | 0.80 | LTA4H (0.45) | LTA4HEPHX2KCNH2 | |
| SCHEMBL2535005 | 0.78 | LTA4H (0.51) | LTA4HEPHX2KCNH2 | |
| SCHEMBL1906619 | 0.78 | LTA4H (0.55) | LTA4HEPHX2KCNH2 | |
| SCHEMBL2532751 | 0.78 | LTA4H (0.55) | LTA4HEPHX2KCNH2 | |
| SCHEMBL1907785 | 0.78 | LTA4H (0.51) | LTA4HEPHX2KCNH2 | |
| SCHEMBL3628094 | 0.76 | LTA4H (0.67) | LTA4HKCNH2 | |
| SCHEMBL1904273 | 0.76 | LTA4H (0.61) | LTA4HEPHX2KCNH2 | |
| SCHEMBL743053 | 0.76 | LTA4H (0.51) | LTA4HEPHX2KCNH2 | |
| SCHEMBL1906910 | 0.76 | LTA4H (0.68) | LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058347-A1 | ARYL-SUBSTITUTED BRIDGED OR FUSED DIAMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |