Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR6 | O00574 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 8/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1905810 | 0.95 | KMT2A (0.58) | CXCR6KMT2AMEN1LTA4HKCNH2 | |
| SCHEMBL12240838 | 0.95 | KMT2A (0.58) | CXCR6KMT2AMEN1LTA4HKCNH2 | |
| SCHEMBL12222541 | 0.95 | KMT2A (0.58) | CXCR6KMT2AMEN1LTA4HKCNH2 | |
| SCHEMBL12222587 | 0.85 | CXCR6 (0.53) | CXCR6KMT2AMEN1LTA4HL3MBTL1 | |
| SCHEMBL1902462 | 0.85 | CXCR6 (0.53) | CXCR6KMT2AMEN1LTA4HL3MBTL1 | |
| SCHEMBL1906229 | 0.82 | LTA4H (0.61) | CXCR6KMT2AMEN1LTA4HKCNH2 | |
| SCHEMBL12222773 | 0.82 | LTA4H (0.61) | CXCR6KMT2AMEN1LTA4HKCNH2 | |
| SCHEMBL12677338 | 0.81 | LTA4H (0.54) | CXCR6LTA4HKCNH2CYP1A2CYP2C19 | |
| SCHEMBL23111727 | 0.81 | LTA4H (0.73) | CXCR6KMT2AMEN1LTA4HKCNH2 | |
| SCHEMBL23111728 | 0.81 | LTA4H (0.73) | CXCR6KMT2AMEN1LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058347-A1 | ARYL-SUBSTITUTED BRIDGED OR FUSED DIAMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |