Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211593 | 0.93 | ALDH1A1 (0.87) | ALDH1A1KMT2AMEN1POLBEPHX2 | |
| SCHEMBL7406370 | 0.87 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1POLBHSD11B1 | |
| SCHEMBL5468343 | 0.85 | ALDH1A1 (0.74) | ALDH1A1KMT2AMEN1POLBEPHX2 | |
| SCHEMBL5468345 | 0.85 | ALDH1A1 (0.74) | ALDH1A1KMT2AMEN1POLBEPHX2 | |
| SCHEMBL6210846 | 0.81 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1POLBEPHX2 | |
| SCHEMBL28224185 | 0.81 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1POLBEPHX2 | |
| SCHEMBL2636523 | 0.79 | MAPT (0.70) | ALDH1A1KMT2AMEN1POLBEPHX2 | |
| SCHEMBL10674722 | 0.79 | CA12 (0.66) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL10717731 | 0.79 | CA12 (0.66) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL6210077 | 0.79 | HSD11B1 (0.86) | ALDH1A1POLBHSD11B1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056693-A1 | NOVEL DERIVATIVES OF N, N'- 2, 4-DIANILINOPYRIMIDINES, PREPARATION THEREOF AS MEDICAMENTS PHARMACEUTICAL COMPOSITIONS AND IN PARTICULAR AS IKK INHIBITORS | SANOFI-AVENTIS (FR) | 2009-05-07 | — | — | WO | disclosed |