Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCK1 | P35558 | 10/20 | 0.49 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13844856 | 0.88 | PCK1 (0.49) | PCK1RORCTHRBADORA2BCNR2 | |
| SCHEMBL3986976 | 0.84 | PCK1 (0.55) | PCK1THRBCNR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3983266 | 0.84 | PCK1 (0.54) | PCK1THRBCNR2MEN1KMT2A | |
| SCHEMBL3986974 | 0.82 | PCK1 (0.47) | PCK1RORCTHRBCNR2MEN1 | |
| SCHEMBL4613426 | 0.80 | PCK1 (0.63) | PCK1RORC | |
| SCHEMBL4615402 | 0.78 | PCK1 (0.42) | PCK1RORCMEN1KMT2A | |
| SCHEMBL3981788 | 0.77 | PKM (0.47) | PCK1RORCADORA2BCNR2MEN1 | |
| SCHEMBL4613128 | 0.72 | PCK1 (0.53) | PCK1 | |
| SCHEMBL4616635 | 0.72 | PCK1 (0.57) | PCK1THRBMEN1KMT2A | |
| SCHEMBL3980723 | 0.70 | PCK1 (0.42) | PCK1RORCTHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515972-B1 | AMIDE SUBSTITUTED XANTHINE DERIVATIVES WITH GLUCONEOGENESIS MODULATING ACTIVITY | HOFFMANN LA ROCHE (CH) | 2009-05-13 | — | — | EP | disclosed |