Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12200871 | 0.88 | GRIK1 (0.36) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL13090405 | 0.83 | GRIK1 (0.32) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL3068622 | 0.80 | ALDH1A1 (0.41) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL3068618 | 0.80 | ALDH1A1 (0.41) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL13845089 | 0.76 | GRIK1 (0.32) | GRIK1GRIK2 | |
| SCHEMBL20381959 | 0.75 | ALDH1A1 (0.39) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL3208533 | 0.74 | ADORA3 (0.40) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL444331 | 0.74 | ADORA3 (0.47) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL3696782 | 0.74 | ADORA3 (0.47) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL3205323 | 0.74 | ADORA3 (0.47) | NR1I2PGRADORA3PTGS2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056983-A1 | NEW DHA DERIVATIVES AND THEIR USE AS MEDICAMENTS | PRONOVA BIOPHARMA NORGE AS (US) | 2009-05-07 | — | — | WO | disclosed |