Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 9/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3845255 | 0.78 | PRKCQ (0.40) | CCNT1PRKCQCYP3A4CYP2C9CYP2D6 | |
| SCHEMBL3984172 | 0.75 | PRKCQ (0.60) | CCNT1PRKCQCYP3A4CYP2C9CYP2D6 | |
| SCHEMBL13608022 | 0.75 | CDK9 (0.42) | CCNT1PRKCQCYP3A4CYP2C9SLC6A2 | |
| SCHEMBL13608017 | 0.74 | CCNT1 (0.45) | CCNT1IRAK1 | |
| SCHEMBL13846484 | 0.73 | PRKCQ (0.49) | CCNT1PRKCQCYP3A4CYP2C9CYP2D6 | |
| SCHEMBL3844951 | 0.69 | CD38 (0.44) | CYP3A4RPS6KB1 | |
| SCHEMBL30137522 | 0.69 | PTPN11 (0.52) | CCNT1KDM1A | |
| SCHEMBL13846476 | 0.67 | PRKCQ (0.60) | PRKCQCYP3A4CYP2C9CYP2D6IRAK1 | |
| SCHEMBL3987070 | 0.67 | PRKCQ (0.70) | PRKCQCYP3A4CYP2C9CYP2D6IRAK1 | |
| SCHEMBL13845174 | 0.67 | PRKCQ (0.48) | PRKCQCYP3A4CYP2C9CYP2D6KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009062059-A2 | ISOMERIC PURINONES AND 1H-IMIDAZOPYRIDINONES AS PKC-THETA INHIBITORS | PHARMACOPEIA, INC. (US) | 2009-05-14 | — | — | WO | disclosed |