SCHEMBL13845261

SCHEMBL13845261

CC(C)(C)OC(=O)Oc1ccc(OCc2ccc(C=C[Si](C)(C)C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.48
PPARA Q07869 2/20 0.48
ELANE P08246 1/20 0.45
OGA O60502 1/20 0.44
GSK3B P49841 5/20 0.42
BACE1 P56817 5/20 0.42
PTPN2 P17706 1/20 0.41
PTPN1 P18031 1/20 0.41
PTPN11 Q06124 1/20 0.41
FFAR1 O14842 1/20 0.41
PPARD Q03181 1/20 0.41
HRH3 Q9Y5N1 1/20 0.40
ABCG2 Q9UNQ0 2/20 0.40
MAOB P27338 1/20 0.40
NR4A2 P43354 1/20 0.40
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
CASP3 P42574 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4052963 0.85 ELANE (0.51) ELANEOGANPC1RAB9ASMN1; SMN2
SCHEMBL4052962 0.85 ELANE (0.51) ELANEOGANPC1RAB9ASMN1; SMN2
SCHEMBL4064604 0.80 ELANE (0.46) ELANEOGANPC1RAB9ASMN1; SMN2
SCHEMBL13845230 0.79 MAOB (0.57) PPARGELANEFFAR1HRH3MAOB
SCHEMBL4054366 0.79 ELANE (0.47) PPARAELANEOGAMAOBNPC1
SCHEMBL4054361 0.79 ELANE (0.47) PPARAELANEOGAMAOBNPC1
SCHEMBL13845257 0.79 ELANE (0.47) PPARAELANEOGAMAOBNPC1
SCHEMBL6276085 0.78 ELANE (0.53) PPARGELANEPTPN2PTPN1PTPN11
SCHEMBL13845260 0.78 MAOB (0.58) PPARGPPARAELANEFFAR1HRH3
SCHEMBL4062398 0.78 MAOB (0.56) PPARGELANEFFAR1MAOBNR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed