SCHEMBL4064604

SCHEMBL4064604

CC(C)(C)OC(=O)Oc1ccc(C(OC(c2ccc(C=C[Si](C)(C)C)cc2)c2ccc(OC(=O)OC(C)(C)C)cc2)c2ccc(C=C[Si](C)(C)C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.46
OGA O60502 1/20 0.43
KDM1A O60341 1/20 0.36
CA2 P00918 1/20 0.34
KMT2A Q03164 5/20 0.33
MAPT P10636 5/20 0.33
LMNA P02545 3/20 0.33
KDM4E B2RXH2 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
MEN1 O00255 3/20 0.33
TTR P02766 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
NPC1 O15118 2/20 0.33
ALDH1A1 P00352 2/20 0.33
RAB9A P51151 2/20 0.33
HIF1A Q16665 1/20 0.33
EPAS1 Q99814 1/20 0.33
MAPKAPK2 P49137 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4052963 0.86 ELANE (0.51) ELANEOGAKDM1ACA2KMT2A
SCHEMBL4052962 0.86 ELANE (0.51) ELANEOGAKDM1ACA2KMT2A
SCHEMBL13845257 0.80 ELANE (0.47) ELANEOGAKDM1ACA2KMT2A
SCHEMBL4054361 0.80 ELANE (0.47) ELANEOGAKDM1ACA2KMT2A
SCHEMBL4054366 0.80 ELANE (0.47) ELANEOGAKDM1ACA2KMT2A
SCHEMBL13845261 0.80 PPARG (0.48) ELANEOGASMN1; SMN2NPC1RAB9A
SCHEMBL4062391 0.79 ELANE (0.55) ELANEKDM1ACA2KMT2ALMNA
SCHEMBL4058207 0.78 ELANE (0.54) ELANEKDM1ACA2KMT2AMAPT
SCHEMBL6391447 0.77 ELANE (0.53) ELANEOGAKDM1ACA2KMT2A
SCHEMBL6391451 0.77 ELANE (0.53) ELANEOGAKDM1ACA2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM ELANE 422/4885OGA 4239/4885KDM1A 113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.