SCHEMBL4054366

SCHEMBL4054366

CC(C)(C)OC(=O)Oc1ccc2cc(C=C[Si](C)(C)C)ccc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.47
CA2 P00918 1/20 0.44
OGA O60502 1/20 0.41
PPARA Q07869 1/20 0.37
KDM1A O60341 1/20 0.36
CYP3A4 P08684 2/20 0.35
KDM4E B2RXH2 5/20 0.35
MAPT P10636 4/20 0.35
HPGD P15428 3/20 0.35
GLA P06280 2/20 0.35
GAA P10253 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HIF1A Q16665 1/20 0.35
MAOB P27338 1/20 0.34
TRPV1 Q8NER1 1/20 0.34
CA12 O43570 3/20 0.34
CA9 Q16790 3/20 0.34
CA1 P00915 1/20 0.34
LMNA P02545 2/20 0.33
KMT2A Q03164 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4054361 1.00 ELANE (0.47) ELANECA2OGAPPARAKDM1A
SCHEMBL13845257 1.00 ELANE (0.47) ELANECA2OGAPPARAKDM1A
SCHEMBL4052963 0.85 ELANE (0.51) ELANECA2OGAKDM1ACYP3A4
SCHEMBL4052962 0.85 ELANE (0.51) ELANECA2OGAKDM1ACYP3A4
SCHEMBL13845254 0.83 ELANE (0.51) ELANECA2OGAPPARAKDM1A
SCHEMBL4054087 0.82 ELANE (0.48) ELANECA2PPARAKDM4EMAPT
SCHEMBL13845255 0.82 ELANE (0.48) ELANECA2PPARAKDM4EMAPT
SCHEMBL4054092 0.82 ELANE (0.48) ELANECA2PPARAKDM4EMAPT
SCHEMBL4061539 0.82 ELANE (0.65) ELANECA2KDM1AKDM4EMAPT
SCHEMBL4064604 0.80 ELANE (0.46) ELANECA2OGAKDM1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM ELANE 422/4885CA2 3704/4885OGA 4239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.