Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 17/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3738791 | 0.91 | KMT2A (0.53) | OPRL1PTGDR2ALDH1A1 | |
| SCHEMBL3735016 | 0.83 | OPRL1 (0.58) | OPRL1ALDH1A1OPRM1OPRK1 | |
| SCHEMBL3738860 | 0.78 | OPRL1 (0.52) | OPRL1ALDH1A1EGLN1 | |
| SCHEMBL3730232 | 0.77 | HSD11B1 (0.50) | OPRL1EGLN1 | |
| SCHEMBL13077798 | 0.77 | KMT2A (0.54) | OPRL1ALDH1A1 | |
| SCHEMBL3742780 | 0.77 | OPRL1 (0.53) | OPRL1OPRM1OPRK1EGLN1 | |
| SCHEMBL3729068 | 0.77 | OPRL1 (0.54) | OPRL1ALDH1A1OPRM1OPRK1EGLN1 | |
| SCHEMBL3736827 | 0.76 | KMT2A (0.51) | OPRL1ALDH1A1EGLN1 | |
| SCHEMBL3733515 | 0.76 | OPRL1 (0.54) | OPRL1PTGDR2ALDH1A1EGLN1 | |
| SCHEMBL3742691 | 0.76 | EGLN1 (0.47) | OPRL1ALDH1A1OPRM1OPRK1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009061676-A2 | ANTAGONISTS OF PGD2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2009-05-14 | — | — | WO | disclosed |