Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3738791 | 0.86 | KMT2A (0.53) | KMT2AALDH1A1L3MBTL1USP2LMNA | |
| SCHEMBL3735016 | 0.85 | OPRL1 (0.58) | KMT2AALDH1A1L3MBTL1USP2LMNA | |
| SCHEMBL13078162 | 0.78 | PKM (0.47) | KMT2AALDH1A1USP2LMNAHTT | |
| SCHEMBL13845879 | 0.77 | OPRL1 (0.49) | ALDH1A1OPRL1 | |
| SCHEMBL13078098 | 0.77 | MEN1 (0.48) | KMT2ATSHRMAPTMEN1OPRL1 | |
| SCHEMBL16812348 | 0.73 | OPRL1 (0.48) | ALDH1A1L3MBTL1LMNAOPRL1 | |
| SCHEMBL13078099 | 0.72 | AOC2 (0.37) | KMT2AALDH1A1L3MBTL1USP2LMNA | |
| SCHEMBL13078159 | 0.71 | L3MBTL1 (0.38) | KMT2AALDH1A1L3MBTL1USP2LMNA | |
| SCHEMBL16812521 | 0.70 | L3MBTL1 (0.38) | KMT2AALDH1A1L3MBTL1LMNAKDM4E | |
| SCHEMBL12362459 | 0.69 | OPRL1 (0.44) | KMT2AALDH1A1L3MBTL1MEN1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280049-A1 | ANTAGONISTS OF PGD2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280049-A1 | ANTAGONISTS OF PGD2 RECEPTORS | PTGDR2, PTGDR, LTB4R2 | KMT2A 4361/4885ALDH1A1 2486/4885L3MBTL1 3732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.