Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 2/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.56 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.46 |
| ▸ | MET | P08581 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.45 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13846145 | 1.00 | HTR4 (0.59) | HTR4ROCK2PKN2TDP1SUV39H2 | |
| SCHEMBL13846092 | 0.93 | HTR4 (0.61) | HTR4ROCK2PKN2TDP1SUV39H2 | |
| SCHEMBL13575608 | 0.93 | HTR4 (0.61) | HTR4ROCK2PKN2TDP1SUV39H2 | |
| SCHEMBL13846100 | 0.93 | HTR4 (0.61) | HTR4ROCK2PKN2TDP1SUV39H2 | |
| SCHEMBL13175546 | 0.88 | HTR4 (0.69) | HTR4TDP1MAPK14 | |
| SCHEMBL13175812 | 0.88 | HTR4 (0.69) | HTR4ROCK2TDP1MAPK14 | |
| SCHEMBL13175544 | 0.87 | TDP1 (0.69) | HTR4TDP1MAPK14 | |
| SCHEMBL13846080 | 0.86 | HTR4 (0.67) | HTR4ROCK2TDP1SUV39H2SMYD3 | |
| SCHEMBL4802575 | 0.86 | HTR4 (0.72) | HTR4ROCK2TDP1MAPK14 | |
| SCHEMBL13845990 | 0.83 | HTR4 (0.57) | HTR4ROCK2TDP1SUV39H2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067547-A1 | POLO-LIKE KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-05-28 | — | — | WO | disclosed |