Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.57 |
| ▸ | PPARA | Q07869 | 20/20 | 0.57 |
| ▸ | PPARD | Q03181 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759675 | 0.85 | PPARG (0.72) | PPARGPPARAPPARD | |
| SCHEMBL13847868 | 0.84 | PPARG (0.52) | PPARGPPARAPPARD | |
| SCHEMBL13847872 | 0.82 | PPARG (0.46) | PPARGPPARAPPARD | |
| SCHEMBL6432402 | 0.76 | PPARG (0.72) | PPARGPPARAPPARD | |
| SCHEMBL13524846 | 0.75 | PPARG (0.55) | PPARGPPARAPPARD | |
| SCHEMBL2815935 | 0.75 | PPARG (0.81) | PPARGPPARAPPARD | |
| SCHEMBL19711226 | 0.74 | PPARG (0.74) | PPARGPPARAPPARD | |
| SCHEMBL5759298 | 0.73 | PPARG (0.85) | PPARGPPARAPPARD | |
| SCHEMBL5741503 | 0.73 | PPARG (0.70) | PPARGPPARAPPARD | |
| SCHEMBL5762327 | 0.73 | PPARG (1.00) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131372-A1 | PHOSPHONATE ANALOGS FOR TREATING METABOLIC DISEASES | CHEN JAMES M | 2009-05-21 | — | — | US | disclosed |
| US-7407965-B2 | Phosphonate analogs for treating metabolic diseases | GILEAD SCIENCES, INC. (US) | 2008-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131372-A1 | PHOSPHONATE ANALOGS FOR TREATING METABOLIC DISEASES | PHOSPHO1, G6PC1, PC | PPARG 314/4885PPARA 234/4885PPARD 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.