Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14161036 | 0.99 | OPRK1 (0.34) | OPRK1OPRM1OPRD1 | |
| SCHEMBL13847990 | 0.88 | OPRM1 (0.33) | OPRK1OPRM1OPRD1 | |
| SCHEMBL13659979 | 0.87 | OPRK1 (0.37) | OPRK1OPRM1OPRD1 | |
| SCHEMBL13659981 | 0.85 | OPRM1 (0.32) | OPRK1OPRM1OPRD1 | |
| SCHEMBL13847989 | 0.85 | OPRM1 (0.34) | OPRK1OPRM1 | |
| SCHEMBL13848227 | 0.83 | OPRM1 (0.47) | OPRK1OPRM1OPRD1 | |
| SCHEMBL13660006 | 0.83 | OPRK1 (0.33) | OPRK1OPRM1OPRD1 | |
| SCHEMBL13962904 | 0.82 | OPRM1 (0.37) | OPRK1OPRM1OPRD1 | |
| SCHEMBL13847987 | 0.81 | OPRM1 (0.38) | OPRK1OPRM1OPRD1 | |
| SCHEMBL13847988 | 0.81 | OPRM1 (0.38) | OPRK1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067275-A1 | N-OXIDES OF 4,5-EPOXY-MORPHINANIUM ANALOGS | PROGENICS PHARMACEUTICALS, INC (US) | 2009-05-28 | — | — | WO | disclosed |