Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28225279 | 0.84 | PDE10A (0.52) | TRPM8SMN1; SMN2MAPTL3MBTL1LMNA | |
| SCHEMBL31689354 | 0.84 | SMN1; SMN2 (0.50) | TRPM8SMN1; SMN2MAPTL3MBTL1LMNA | |
| SCHEMBL16258603 | 0.78 | PDGFRB (0.50) | TRPM8SMN1; SMN2MAPTL3MBTL1LMNA | |
| SCHEMBL13842542 | 0.76 | P2RX3 (0.75) | P2RX3P2RX2 | |
| SCHEMBL17051050 | 0.76 | RAB9A (0.47) | SMN1; SMN2MAPTL3MBTL1LMNANPC1 | |
| SCHEMBL27316536 | 0.76 | P2RX3 (0.53) | MAPTHSD17B10GAAPOLBP2RX3 | |
| SCHEMBL20150104 | 0.74 | SMN1; SMN2 (0.45) | TRPM8SMN1; SMN2MAPTL3MBTL1LMNA | |
| SCHEMBL2039527 | 0.73 | SMN1; SMN2 (0.62) | SMN1; SMN2MAPTL3MBTL1LMNAKDM4E | |
| SCHEMBL8227726 | 0.73 | KDM4E (0.50) | SMN1; SMN2MAPTL3MBTL1LMNAKDM4E | |
| SCHEMBL29496935 | 0.73 | SMN1; SMN2 (0.62) | SMN1; SMN2MAPTL3MBTL1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |