Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848454 | 0.91 | NPC1 (0.44) | TLR7NPC1TP53HPGDRAB9A | |
| SCHEMBL4061183 | 0.89 | NPC1 (0.41) | TLR7NPC1TP53RAB9ATLR8 | |
| SCHEMBL13848453 | 0.88 | KDM4E (0.45) | TLR7NPC1TP53HPGDRAB9A | |
| SCHEMBL13848385 | 0.84 | TSHR (0.44) | NPC1TP53HPGDRAB9AHRH3 | |
| SCHEMBL13848380 | 0.83 | CARM1 (0.32) | — | |
| SCHEMBL13848084 | 0.83 | TSHR (0.46) | TLR7NPC1TP53HPGDRAB9A | |
| SCHEMBL13848456 | 0.83 | AGTR2 (0.44) | — | |
| SCHEMBL4067194 | 0.82 | MEN1 (0.41) | NPC1RAB9AHRH3DRD4DRD2 | |
| SCHEMBL13848378 | 0.82 | RAB9A (0.47) | TLR7NPC1TP53HPGDRAB9A | |
| SCHEMBL4378118 | 0.82 | HSP90AA1 (0.47) | KDRPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |