Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 13/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848456 | 0.91 | AGTR2 (0.44) | CYP19A1AGTR2LMNASMN1; SMN2CYP11B1 | |
| SCHEMBL4373611 | 0.87 | FNTA (0.46) | CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL13848375 | 0.84 | MAPT (0.35) | CYP19A1LMNAKDM4EKMT2A | |
| SCHEMBL13848385 | 0.83 | TSHR (0.44) | SMN1; SMN2KMT2A | |
| SCHEMBL13848084 | 0.82 | TSHR (0.46) | SMN1; SMN2KMT2A | |
| SCHEMBL13848378 | 0.82 | RAB9A (0.47) | SMN1; SMN2KMT2A | |
| SCHEMBL13848454 | 0.82 | NPC1 (0.44) | SMN1; SMN2KDM4EGAAKMT2A | |
| SCHEMBL13848067 | 0.81 | HSP90AA1 (0.47) | CYP19A1AGTR2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL13848091 | 0.80 | IDO1 (0.39) | CYP19A1SMN1; SMN2KMT2A | |
| SCHEMBL13848452 | 0.80 | MAPK14 (0.37) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |