SCHEMBL13848423

SCHEMBL13848423

CN1C(=O)C(=Cc2ccccc2)C(=O)N(C)C1=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.65
KDM4E B2RXH2 2/20 0.65
EP300 Q09472 1/20 0.63
CA12 O43570 1/20 0.60
CA1 P00915 1/20 0.60
CA2 P00918 1/20 0.60
CA7 P43166 1/20 0.60
CA9 Q16790 1/20 0.60
ALDH1A1 P00352 6/20 0.57
KMT2A Q03164 6/20 0.57
MEN1 O00255 5/20 0.57
RECQL P46063 1/20 0.57
KDM4C Q9H3R0 1/20 0.57
XDH P47989 1/20 0.57
CISD1 Q9NZ45 2/20 0.53
MAOA P21397 1/20 0.53
MAOB P27338 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
POLB P06746 1/20 0.51
ERBB2 P04626 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17717968 0.90 CA12 (0.71) MAPTKDM4EEP300CA12CA1
SCHEMBL31424240 0.89 CA12 (0.58) MAPTKDM4EEP300CA12CA1
SCHEMBL7432799 0.88 EP300 (0.62) MAPTKDM4EEP300CA12CA1
SCHEMBL7432791 0.88 EP300 (0.62) MAPTKDM4EEP300CA12CA1
SCHEMBL17717936 0.86 MAPT (0.63) MAPTKDM4EEP300CA12CA1
SCHEMBL16979817 0.86 EP300 (0.66) MAPTKDM4EEP300CA12CA1
SCHEMBL2719600 0.85 CA12 (0.54) MAPTKDM4EEP300CA12CA1
SCHEMBL15044605 0.82 MAPT (0.65) MAPTKDM4EEP300CA12CA1
SCHEMBL13751815 0.81 CA12 (0.61) MAPTKDM4EEP300CA12CA1
SCHEMBL24077379 0.78 CA12 (0.58) MAPTKDM4EEP300CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119735614-A 1-Phosphanorbornene-dimethyl xanthene chiral ligand and synthetic method and application thereof 河南工业大学 2025-04-01 CN disclosed
CN-119431387-A Spirobarbituric acid-epoxyhexane compound and synthetic method and application thereof 河南工业大学 2025-02-14 CN disclosed
EP-4383990-A1 MATERIALS FOR OPTOELECTRONIC APPLICATIONS The Regents Of The University Of Michigan (US) 2024-06-12 EP disclosed
CN-117836333-A Free radically polymerizable composition, method of polymerization, and polymerized composition 3M创新有限公司 2024-04-05 CN disclosed
WO-2023031719-A1 FREE-RADICALLY POLYMERIZABLE COMPOSITION, METHOD OF POLYMERIZING THE SAME, AND POLYMERIZED COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-03-09 WO disclosed
CN-108358831-B Polysubstituted carbazole derivative and preparation method thereof 山东师范大学 2020-09-29 CN disclosed
US-8900785-B2 Charge control agent and toner using the same HODOGAYA CHEMICAL CO., LTD. (JP) 2014-12-02 US disclosed
US-8900785-B2 Charge control agent and toner using the same HODOGAYA CHEMICAL CO., LTD. (JP) 2014-12-02 US disclosed
US-8900785-B2 Charge control agent and toner using the same HODOGAYA CHEMICAL CO., LTD. (JP) 2014-12-02 US disclosed
CN-103238117-A Charge control agent and toner using same HODOGAYA CHEMICAL CO LTD 2013-08-07 CN disclosed
EP-2618219-A1 CHARGE CONTROL AGENT AND TONER USING SAME Hodogaya Chemical Co., Ltd. (JP) 2013-07-24 EP disclosed
EP-2618219-A1 CHARGE CONTROL AGENT AND TONER USING SAME Hodogaya Chemical Co., Ltd. (JP) 2013-07-24 EP disclosed
US-20130157190-A1 CHARGE CONTROL AGENT AND TONER USING THE SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2013-06-20 US disclosed
US-20130157190-A1 CHARGE CONTROL AGENT AND TONER USING THE SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2013-06-20 US disclosed
US-20130157190-A1 CHARGE CONTROL AGENT AND TONER USING THE SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2013-06-20 US disclosed
EP-1305026-B1 BARBITURIC ACID ANALOGS AS THERAPEUTIC AGENTS NOVUSPHARMA SPA (IT) 2009-05-13 EP disclosed
US-20080113993-A1 BARBITURIC ACID ANALOGS AS THERAPEUTIC AGENTS VIA ARIOSTO, 23 (IT) 2008-05-15 US disclosed
US-20080113993-A1 BARBITURIC ACID ANALOGS AS THERAPEUTIC AGENTS VIA ARIOSTO, 23 (IT) 2008-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080113993-A1 BARBITURIC ACID ANALOGS AS THERAPEUTIC AGENTS HIF1A, HIF1AN, PDGFA MAPT 3423/4885KDM4E 688/4885EP300 4/4885
US-20130157190-A1 CHARGE CONTROL AGENT AND TONER USING THE SAME GABRR1, GABRR2, GABRR3 MAPT 1617/4885KDM4E 753/4885EP300 1531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.