Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13744438 | 0.87 | CYP2A6 (0.42) | CYP2A6CYP3A4CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL24623245 | 0.83 | ADRB2 (0.50) | CYP2A6CYP3A4CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL13744630 | 0.83 | ENPP3 (0.42) | ALDH1A1RAB9ALMNAMEN1MAPT | |
| SCHEMBL13848516 | 0.81 | S1PR1 (0.39) | CYP19A1ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL24624120 | 0.81 | CYP2A6 (0.44) | CYP2A6CYP3A4CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL13744533 | 0.75 | HTR2C (0.33) | — | |
| SCHEMBL9346559 | 0.74 | CYP2A6 (0.54) | CYP2A6CYP3A4CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL13484397 | 0.74 | ADORA2A (0.38) | CYP2C19ALDH1A1CYP1A2MEN1MAPT | |
| SCHEMBL13484328 | 0.73 | TSHR (0.46) | CYP2C9CYP2C19CYP19A1ALDH1A1CYP1A2 | |
| SCHEMBL13984428 | 0.71 | HSP90AA1 (0.53) | CYP2A6CYP3A4CYP2E1CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549624-B1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | SCRIPPS RESEARCH INST (US) | 2009-05-13 | — | — | EP | disclosed |