SCHEMBL13848657

SCHEMBL13848657

CCc1ncc(-c2cocn2)o1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.39
NOTUM Q6P988 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13744496 0.73 FAAH (0.36) FAAH
SCHEMBL8242668 0.70 FAAH (0.46) FAAH
SCHEMBL1696557 0.67 NOTUM (0.68) NOTUM
SCHEMBL22388750 0.66 SCN9A (0.37)
SCHEMBL684672 0.65
SCHEMBL12091036 0.64 FAAH (0.43) FAAHNOTUM
SCHEMBL1617734 0.64 RAB9A (0.51) FAAHNOTUM
SCHEMBL7903330 0.64 NOTUM (0.70) NOTUM
SCHEMBL11519618 0.63
SCHEMBL3265214 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1549624-B1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE SCRIPPS RESEARCH INST (US) 2009-05-13 EP disclosed