SCHEMBL1384932

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1386407	0.88	MAPK14 (0.52)	ADORA2AADORA2BADORA1MAPK14MAPK13
	SCHEMBL1384875	0.85	MAPK14 (0.45)	ADORA2AADORA2BADORA1MAPK14MAPK13
	SCHEMBL4054613	0.83	ADORA2B (0.67)	ADORA2AADORA2BADORA1LMNACCNT1
	SCHEMBL1383884	0.81	MAPK14 (0.46)	AKT1AKT2MAPK14MAPK13MAPK12
	SCHEMBL6132086	0.80	TGFBR1 (0.50)	AKT1MAPK14MAPK13MAPK12MAPK11
	SCHEMBL29894085	0.78	ADORA2A (0.67)	ADORA2AADORA2BADORA1AKT1MAPK14
	SCHEMBL2933510	0.77	RPS6KB1 (0.52)	AKT2MAPK14MAPK13MAPK12MAPK11
	SCHEMBL2926500	0.77	DYRK1A (0.47)	ADORA2AADORA2BADORA1AKT1AKT2
	SCHEMBL2933513	0.77	RPS6KB1 (0.52)	AKT2MAPK14MAPK13MAPK12MAPK11
	SCHEMBL6070097	0.76	TGFBR1 (0.60)	AKT1AKT2MAPK14MAPK13MAPK12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.