Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.47 |
| ▸ | TYR | P14679 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11942564 | 0.98 | ALOX5 (0.44) | ALOX5TYRMEN1TP53CYP3A4 | |
| SCHEMBL19658854 | 0.92 | TYR (0.44) | ALOX5TYRMEN1TP53CYP3A4 | |
| SCHEMBL15325843 | 0.84 | F2RL1 (0.41) | MAPTHTTPTGS2SLC6A2SLC6A4 | |
| SCHEMBL21392022 | 0.83 | ALOX5 (0.49) | ALOX5TYRMEN1TP53CYP3A4 | |
| SCHEMBL20350112 | 0.83 | TYR (0.49) | ALOX5TYRMEN1TP53CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL14719246 | 0.82 | F2RL1 (0.40) | MAPTHTTPTGS2SLC6A2SLC6A4 | |
| SCHEMBL13763 | 0.81 | MPO (0.51) | SLC6A2SLC6A4SLC6A3MPO | |
| SCHEMBL3892982 | 0.81 | TAAR1 (0.57) | ALOX5TYRMEN1TP53CYP3A4 | |
| SCHEMBL9699152 | 0.81 | TAAR1 (0.57) | ALOX5TYRMEN1TP53CYP3A4 | |
| SCHEMBL11241677 | 0.81 | TAAR1 (0.57) | ALOX5TYRMEN1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2062879-A1 | Heterocyclic inhibitors of p38 | Vertex Pharmceuticals Incorporated (US) | 2009-05-27 | — | — | EP | disclosed |