Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7493903 | 0.78 | CA2 (0.53) | CA2KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL7786492 | 0.77 | GRIN2D (0.48) | CA2KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL2558670 | 0.77 | CA2 (0.49) | CA2KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL10102730 | 0.75 | CHEK2 (0.44) | KDM4EHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL13849673 | 0.74 | KDM4E (0.52) | KDM4EHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL10704493 | 0.74 | CA2 (0.49) | CA2KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL6190850 | 0.73 | FYN (0.44) | CA2KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL8980508 | 0.71 | AKR1B1 (0.51) | CA2KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL10102698 | 0.71 | KDM4E (0.37) | KDM4EHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL28531473 | 0.71 | GRIN2D (0.57) | KDM4EHPGDKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131412-A1 | NOVEL 2-QUINOLONE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131412-A1 | NOVEL 2-QUINOLONE DERIVATIVE | SCN1B, OPRL1, SCN1A | CA2 3224/4885KDM4E 2702/4885HPGD 933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.