Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985814 | 0.81 | KDM4E (0.49) | KDM4EHSD17B10KMT2AMAPK1HTT | |
| SCHEMBL10319865 | 0.77 | DYRK1A (0.61) | KDM4EHSD17B10HPGDALDH1A1GAA | |
| SCHEMBL6306443 | 0.77 | KDM4E (0.45) | KDM4EHSD17B10KMT2ASMN1; SMN2HPGD | |
| SCHEMBL7377635 | 0.75 | KDM4E (0.61) | KDM4EHSD17B10KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL13850474 | 0.74 | CA2 (0.51) | KDM4EHSD17B10KMT2AHPGDMEN1 | |
| SCHEMBL23625932 | 0.74 | KDM4E (0.65) | KDM4EHSD17B10KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL30952894 | 0.74 | KDM4E (0.65) | KDM4EHSD17B10KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL30952932 | 0.74 | KDM4E (0.65) | KDM4EHSD17B10KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL10330638 | 0.72 | KDM4E (0.61) | KDM4EHSD17B10KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL12082628 | 0.72 | ALDH1A1 (0.61) | KDM4EHSD17B10KMT2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131412-A1 | NOVEL 2-QUINOLONE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-05-21 | — | — | US | disclosed |
| EP-1908752-A1 | NOVEL 2-QUINOLONE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131412-A1 | NOVEL 2-QUINOLONE DERIVATIVE | SCN1B, OPRL1, SCN1A | KDM4E 2702/4885HSD17B10 3491/4885KMT2A 2423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.