Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387045 | 0.90 | LPAR1 (0.38) | ATMSLC2A1LPAR1LPAR5C5AR1 | |
| SCHEMBL1386968 | 0.86 | MEN1 (0.37) | LMNAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5526790 | 0.86 | SLC2A1 (0.36) | LMNAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12521133 | 0.85 | LMNA (0.41) | LMNAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5189096 | 0.84 | ADRB1 (0.35) | LMNAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12521103 | 0.84 | LMNA (0.40) | LMNAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5531836 | 0.84 | SLC2A1 (0.37) | MEN1KMT2ASLC2A1HDAC8HDAC1 | |
| SCHEMBL5524589 | 0.84 | GRM5 (0.40) | LMNAKMT2ASLC2A1HDAC8HDAC1 | |
| SCHEMBL12521286 | 0.84 | LMNA (0.51) | LMNAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12521079 | 0.84 | LMNA (0.44) | LMNAMEN1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4787254-B2 | — | — | 2011-10-05 | — | — | JP | claimed |