Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13853146 | 0.89 | HDAC6 (0.41) | HDAC6L3MBTL1 | |
| SCHEMBL8827200 | 0.88 | HDAC6 (0.37) | HDAC6PLA2G7 | |
| SCHEMBL13853160 | 0.88 | HDAC6 (0.50) | HDAC6L3MBTL1PLA2G7CYP19A1 | |
| Ethylene Glycol SCHEMBL9177359 | 0.86 | HDAC6 (0.36) | HDAC6PLA2G7 | |
| SCHEMBL29303859 | 0.83 | HDAC6 (0.38) | HDAC6L3MBTL1PLA2G7BRD4 | |
| SCHEMBL13853163 | 0.82 | HDAC6 (0.42) | HDAC6L3MBTL1PLA2G7CYP19A1 | |
| SCHEMBL11852383 | 0.79 | HDAC6 (0.33) | HDAC6PLA2G7 | |
| SCHEMBL112156 | 0.77 | ALDH1A1 (0.43) | HDAC6L3MBTL1 | |
| SCHEMBL27596669 | 0.77 | HDAC6 (0.41) | HDAC6L3MBTL1CYP19A1 | |
| SCHEMBL30503758 | 0.76 | BRD4 (0.33) | HDAC6L3MBTL1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090121251-A1 | Siloxane-hydantoin copolymer, optoelectronic device encapsulated therewith and method | LUMINATION LLC | 2009-05-14 | — | — | US | disclosed |