SCHEMBL112156

SCHEMBL112156

O=C1CN(CCCO)C(=O)N1CCCO

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
KMT2A Q03164 6/20 0.43
PABPC1 P11940 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HTT P42858 3/20 0.40
TSHR P16473 3/20 0.40
USP2 O75604 2/20 0.40
HSD17B10 Q99714 1/20 0.40
KDM4E B2RXH2 4/20 0.36
HDAC6 Q9UBN7 5/20 0.35
MEN1 O00255 3/20 0.35
RECQL P46063 2/20 0.35
RGS12 O14924 1/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CNR1 P21554 1/20 0.31
ATM Q13315 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8827200 0.83 HDAC6 (0.37) KMT2AKDM4EHDAC6HDAC1HDAC2
SCHEMBL16068394 0.83
Ethylene Glycol SCHEMBL9177359 0.82 HDAC6 (0.36) KMT2AKDM4EHDAC6HDAC1HDAC2
SCHEMBL9190811 0.80 PLA2G7 (0.46) ALDH1A1KMT2APABPC1L3MBTL1HTT
SCHEMBL11608984 0.80 HEXA (0.35) KMT2AUSP2KDM4EHDAC6MEN1
SCHEMBL14258605 0.80 KMT2A (0.35) ALDH1A1KMT2APABPC1L3MBTL1HTT
SCHEMBL221915 0.78 MGLL (0.46) ALDH1A1HDAC6MAPT
SCHEMBL11852383 0.78 HDAC6 (0.33) KMT2AKDM4EHDAC6HDAC1HDAC2
SCHEMBL13853145 0.77 HDAC6 (0.46) L3MBTL1HDAC6
SCHEMBL8338718 0.77 KMT2A (0.49) ALDH1A1KMT2APABPC1L3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12173178-B2 Polyfunctional hydrazide crosslinker PPG INDUSTRIES OHIO, INC. (US) 2024-12-24 US disclosed
US-20240117215-A1 POLYFUNCTIONAL HYDRAZIDE CROSSLINKER PPG INDUSTRIES OHIO, INC. (US) 2024-04-11 US disclosed
US-20230220219-A1 COMPOSITIONS CONTAINING THERMALLY CONDUCTIVE FILLERS PPG INDUSTRIES OHIO, INC. (US) 2023-07-13 US disclosed
US-20230120549-A1 Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same PPG INDUSTRIES OHIO, INC. 2023-04-20 US disclosed
US-11591436-B2 Polyurethane article and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2023-02-28 US disclosed
CN-115702189-A Composition containing thermally conductive filler PPG工业俄亥俄公司 2023-02-14 CN disclosed
US-11472912-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2022-10-18 US disclosed
US-20220119581-A1 Aircraft Windows PPG INDUSTRIES, INC. 2022-04-21 US disclosed
US-20220112328-A1 \"Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same\ PPG INDUSTRIES OHIO, INC. 2022-04-14 US disclosed
US-11248083-B2 Aircraft windows PPG INDUSTRIES OHIO, INC. (US) 2022-02-15 US disclosed
US-4798745-A CROSSLINKING A MALEIC ANHYDRIDE COPOLYMER PPG INDUSTRIES, INC. (US) 1989-01-17 US disclosed
US-4798746-A Basecoat/clearcoat method of coating utilizing an anhydride additive in the thermoplastic polymer-containing basecoat for improved repairability PPG INDUSTRIES, INC. (US) 1989-01-17 US disclosed
US-4749803-A Reaction products of mercapto-functional monohydric alcohols and vinyl silanes, and NCO-functional compounds therefrom PPG INDUSTRIES, INC. (US) 1988-06-07 US disclosed
US-4720534-A NCO-terminated compounds from adducts of mercapto-functional polyhydric alcohols and vinyl-type silanes containing hydrolyzable groups PPG INDUSTRIES, INC. (US) 1988-01-19 US disclosed
EP-0231514-A2 Compositions based on resins having silicon atoms attached to hydrolyzable groups derived from vinyl silanes and mercaptofunctional compounds PPG INDUSTRIES, INC. (US) 1987-08-12 EP disclosed
EP-0229390-A2 Reaction products of mercapto-functional monohydric alcohols and vinyl silanes, and NCO-functional compounds therefrom PPG INDUSTRIES, INC. (US) 1987-07-22 EP disclosed
US-4652610-A FLEXIBLE COATINGS; AUTOMOBILE PAINTS PPG INDUSTRIES, INC. (US) 1987-03-24 US disclosed
US-4652664-A Addition products prepared from mercapto-functional polyhydric alcohols and vinyl-type silanes containing hydrolyzable groups PPG INDUSTRIES, INC. (US) 1987-03-24 US disclosed
EP-0212063-A1 Urethane resins containing hydrolyzable moieties from organosilane compounds PPG INDUSTRIES, INC. (US) 1987-03-04 EP disclosed
US-4622369-A Urethane resins containing hydrolyzable moieties from organosilane compounds PPG INDUSTRIES, INC. (US) 1986-11-11 US disclosed