Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
| ▸ | PLEC | Q15149 | 1/20 | 0.72 |
| ▸ | ALPL | P05186 | 1/20 | 0.60 |
| ▸ | ALPI | P09923 | 1/20 | 0.60 |
| ▸ | ALPG | P10696 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9883329 | 0.84 | USP2 (0.77) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL14044262 | 0.84 | USP2 (0.77) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL940682 | 0.84 | MEN1 (1.00) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL15502020 | 0.83 | USP2 (0.72) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL13314111 | 0.83 | USP2 (0.56) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL14771583 | 0.82 | USP2 (0.64) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL10082363 | 0.82 | USP2 (0.73) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL7824274 | 0.82 | USP2 (0.77) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL12639226 | 0.81 | USP2 (0.66) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL10167876 | 0.81 | MEN1 (0.72) | USP2MEN1KMT2APOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090123373-A1 | AMYLOID-IMAGING AGENTS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR NIH | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090123373-A1 | AMYLOID-IMAGING AGENTS | APBA1, APP, MAPT | USP2 2090/4885MEN1 959/4885KMT2A 4251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.