SCHEMBL14044262

SCHEMBL14044262

Cc1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 3/20 0.77
MEN1 O00255 3/20 0.77
KMT2A Q03164 3/20 0.77
POLB P06746 2/20 0.77
ATM Q13315 1/20 0.77
PLEC Q15149 1/20 0.77
ALPL P05186 1/20 0.64
ALPI P09923 1/20 0.64
ALPG P10696 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.57
CA12 O43570 3/20 0.56
CA9 Q16790 3/20 0.56
ESR1 P03372 2/20 0.51
ESR2 Q92731 2/20 0.51
CSNK2A2 P19784 1/20 0.50
CSNK2B P67870 1/20 0.50
CSNK2A1 P68400 1/20 0.50
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 2/20 0.48
CYP3A4 P08684 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9883329 0.87 USP2 (0.77) USP2MEN1KMT2APOLBATM
SCHEMBL940682 0.87 MEN1 (1.00) USP2MEN1KMT2APOLBATM
SCHEMBL10167876 0.86 MEN1 (0.72) USP2MEN1KMT2APOLBATM
SCHEMBL10031002 0.86 USP2 (0.72) USP2MEN1KMT2APOLBATM
SCHEMBL14044263 0.86 MEN1 (0.76) USP2MEN1KMT2APOLBATM
SCHEMBL10030600 0.86 USP2 (0.64) USP2MEN1KMT2APOLBATM
SCHEMBL10082363 0.85 USP2 (0.73) USP2MEN1KMT2APOLBATM
SCHEMBL12909281 0.85 USP2 (0.62) USP2MEN1KMT2APOLBATM
SCHEMBL7824274 0.85 USP2 (0.77) USP2MEN1KMT2APOLBATM
SCHEMBL12909301 0.84 USP2 (0.68) USP2MEN1KMT2APOLBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170082642-A1 FLUORESCENT CELL MARKERS KODE BIOTECH LTD (NZ) 2017-03-23 US disclosed
US-7439035-B1 Method of identifying or characterizing a compound that modulates ribonuclease H activity MCGILL UNIVERSITY (CA) 2008-10-21 US disclosed
US-7186520-B1 Substrate for assaying ribonuclease H activity MCGILL UNIVERSITY (CA) 2007-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170082642-A1 FLUORESCENT CELL MARKERS PTDSS2, SPTLC2, CD69 USP2 1329/4885MEN1 1577/4885KMT2A 3441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.