SCHEMBL940682

SCHEMBL940682

O=c1ccc2c(-c3ccccc3)c3ccc(O)cc3oc-2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
USP2 O75604 3/20 1.00
POLB P06746 2/20 1.00
ATM Q13315 1/20 1.00
PLEC Q15149 1/20 1.00
ALPL P05186 1/20 0.66
ALPI P09923 1/20 0.66
ALPG P10696 1/20 0.66
L3MBTL1 Q9Y468 1/20 0.62
CA12 O43570 2/20 0.58
AKR1B1 P15121 2/20 0.58
MAOA P21397 2/20 0.58
MAOB P27338 2/20 0.58
HSD17B3 P37058 2/20 0.58
CA9 Q16790 2/20 0.58
CALM1 P0DP23 2/20 0.58
PKM P14618 2/20 0.58
FTO Q9C0B1 2/20 0.58
AKR1B10 O60218 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7824274 0.87 USP2 (0.77) MEN1KMT2AUSP2POLBATM
SCHEMBL14044262 0.87 USP2 (0.77) MEN1KMT2AUSP2POLBATM
SCHEMBL9883329 0.87 USP2 (0.77) MEN1KMT2AUSP2POLBATM
SCHEMBL13320830 0.87 USP2 (0.76) MEN1KMT2AUSP2POLBATM
SCHEMBL29974216 0.87 USP2 (0.76) MEN1KMT2AUSP2POLBATM
SCHEMBL13425295 0.86 MEN1 (0.76) MEN1KMT2AUSP2POLBATM
SCHEMBL14044263 0.86 MEN1 (0.76) MEN1KMT2AUSP2POLBATM
SCHEMBL8930410 0.85 MEN1 (0.74) MEN1KMT2AUSP2POLBATM
SCHEMBL10082363 0.85 USP2 (0.73) MEN1KMT2AUSP2POLBATM
SCHEMBL9351057 0.84 MEN1 (0.72) MEN1KMT2AUSP2POLBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3373009-A1 FLUORESCENT COMPOUNDS FOR THE DETECTION OF MALIGNANT MELANOMA Karlsruher Institut für Technologie (DE) 2018-09-12 EP claimed
WO-2023172102-A1 BODIPY DERIVATIVE COMPOUND AND FLUORESCENT PROBE FOR DETECTING CHANGES IN PH AND VISCOSITY OF OIL COMPRISING SAME 기초과학연구원 2023-09-14 WO disclosed
US-11352325-B2 Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals WATERS TECHNOLOGIES CORPORATION (US) 2022-06-07 US disclosed
WO-2021052934-A1 OPTICAL PH SENSOR Abberior GmbH (DE) 2021-03-25 WO disclosed
EP-3373009-A1 FLUORESCENT COMPOUNDS FOR THE DETECTION OF MALIGNANT MELANOMA Karlsruher Institut für Technologie (DE) 2018-09-12 EP disclosed
US-20160169850-A1 SENSOR MOLECULE UNIV MALTA (MT) 2016-06-16 US disclosed
US-20160166679-A1 METHOD OF TREATMENT USING FOLATE CONJUGATES AND TYROSINE KINASE INHIBITORS PURDUE RESEARCH FOUNDATION 2016-06-16 US disclosed
US-9365614-B2 IAP BIR domain binding compounds PHARMASCIENCE INC. (CA) 2016-06-14 US disclosed
US-20160139136-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS WATERS TECHNOLOGIES CORPORATION (US) 2016-05-19 US disclosed
US-9284350-B2 IAP BIR domain binding compounds PHARMASCIENCE INC. (CA) 2016-03-15 US disclosed
US-5629453-A Process for the manufacture of hydroxyalkoxybenzophenones GREAT LAKES CHEMICAL FRANCE (FR) 1997-05-13 US disclosed
EP-0721929-A1 Process for the manufacture of hydroxyalkoxybenzophenones GREAT LAKES CHEMICAL FRANCE S.A. (FR) 1996-07-17 EP disclosed
EP-0157384-B1 Substrates for hydrolases, process for their preparation and their use BIOMED LABORDIAGNOSTIK GMBH (DE) 1995-01-18 EP disclosed
EP-0154092-B1 PROCESS FOR THE PREPARATION OF 2,4-DIHYDROXYBENZOPHENONES GAF CORPORATION (US) 1988-05-25 EP disclosed
US-4716222-A CHROMOGENS, SPECTROPHOTOMETRY HOECHST AKTIENGESELLSCHAFT (DE) 1987-12-29 US disclosed
US-4568429-A Process for the preparation of 2,4-dihydroxybenzophenones GAF CORPORATION (US) 1986-02-04 US disclosed
EP-0050684-B1 NOVEL ETHER SUBSTITUTED FLUORESCEIN COMPOUNDS AS FLUORESCERS AND QUENCHERS SYVA COMPANY (US) 1986-01-22 EP disclosed
EP-0157384-A2 Substrates for hydrolases, process for their preparation and their use Biomed Labordiagnostik GmbH (DE) 1985-10-09 EP disclosed
EP-0050684-A1 Novel ether substituted fluorescein compounds as fluorescers and quenchers SYVA COMPANY (US) 1982-05-05 EP disclosed
US-4318846-A RADIOIMMUNOASSAY SYVA COMPANY (US) 1982-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160166679-A1 METHOD OF TREATMENT USING FOLATE CONJUGATES AND TYROSINE KINASE INHIBITORS DHFR, FOLR1, FER MEN1 1476/4885KMT2A 558/4885USP2 2489/4885
US-11352325-B2 Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals FUT5, FUT6, ST3GAL3 MEN1 1473/4885KMT2A 2994/4885USP2 3657/4885
US-20160139136-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS FUT5, FUT6, CSGALNACT1 MEN1 2746/4885KMT2A 3081/4885USP2 2267/4885
US-20160169850-A1 SENSOR MOLECULE QSOX1, AOX1, SCO2 MEN1 4300/4885KMT2A 4705/4885USP2 4414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.