Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13853971 | 0.94 | HTT (0.58) | HTTTGM2KEAP1NFE2L2LMNA | |
| SCHEMBL1439677 | 0.85 | LMNA (0.57) | HTTTGM2KEAP1NFE2L2LMNA | |
| SCHEMBL9202853 | 0.85 | HTT (0.55) | HTTTGM2KEAP1NFE2L2LMNA | |
| SCHEMBL13725441 | 0.83 | HTT (0.59) | HTTTGM2KEAP1NFE2L2LMNA | |
| SCHEMBL9204222 | 0.82 | LMNA (0.53) | HTTTGM2KEAP1NFE2L2LMNA | |
| SCHEMBL7282990 | 0.81 | HSD17B10 (0.56) | HTTLMNASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL24486765 | 0.80 | HTT (0.65) | HTTTGM2KEAP1NFE2L2LMNA | |
| SCHEMBL18254066 | 0.79 | HTT (0.81) | HTTTGM2KEAP1NFE2L2LMNA | |
| SCHEMBL1442202 | 0.79 | LMNA (0.56) | HTTTGM2KEAP1NFE2L2LMNA | |
| SCHEMBL1440479 | 0.79 | LMNA (0.56) | HTTTGM2KEAP1NFE2L2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090123507-A1 | Metal Oxide Nanoparticles Coated With Specific N-Acylaminomethylene Phosphonates | CIBA SPECIALTY CHEMICALS CORP. | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090123507-A1 | Metal Oxide Nanoparticles Coated With Specific N-Acylaminomethylene Phosphonates | PHOSPHO1, ACP1, PNN | HTT 2508/4885TGM2 2740/4885KEAP1 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.