Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2238914 | 0.79 | CYP2D6 (0.66) | KEAP1NFE2L2CHRM2CHRM1CHRM3 | |
| SCHEMBL13429177 | 0.78 | KEAP1 (0.56) | KEAP1NFE2L2CHRM2CHRM1CHRM3 | |
| SCHEMBL13131231 | 0.78 | KEAP1 (0.56) | KEAP1NFE2L2CHRM2CHRM1CHRM3 | |
| SCHEMBL9906166 | 0.78 | KEAP1 (0.56) | KEAP1NFE2L2CHRM2CHRM1CHRM3 | |
| SCHEMBL18415154 | 0.78 | KEAP1 (0.56) | KEAP1NFE2L2CHRM2CHRM1CHRM3 | |
| SCHEMBL9940816 | 0.76 | KEAP1 (0.55) | KEAP1NFE2L2CHRM2CHRM1CHRM3 | |
| SCHEMBL198459 | 0.76 | MAPT (0.52) | KEAP1NFE2L2CHRM2CHRM1CHRM3 | |
| SCHEMBL12531908 | 0.76 | MAPT (0.52) | KEAP1NFE2L2CHRM2CHRM1CHRM3 | |
| SCHEMBL2683059 | 0.76 | KEAP1 (0.50) | KEAP1NFE2L2CHRM2CHRM1CHRM3 | |
| SCHEMBL17771882 | 0.75 | KEAP1 (0.58) | KEAP1NFE2L2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4838934-B2 | — | — | 2011-12-14 | — | — | JP | claimed |
| EP-1042291-A1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | Klinge Pharma GmbH (DE) | 2000-10-11 | — | — | EP | claimed |
| WO-1999031064-A1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | KLINGE PHARMA GMBH (DE) | 1999-06-24 | — | — | WO | claimed |
| US-7232640-B1 | Positive resist composition | FUJIFILM CORPORATION (JP) | 2007-06-19 | — | — | US | disclosed |
| US-20070128547-A1 | POSITIVE RESIST COMPOSITION | FUJI PHOTO FILM CO., LTD. | 2007-06-07 | — | — | US | disclosed |