SCHEMBL1385653

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6329907	0.89	MCL1 (0.80)	MCL1KDM4EALDH1A1GPR35TTR
	SCHEMBL3498475	0.88	MCL1 (0.78)	MCL1KDM4EALDH1A1GPR35TTR
	SCHEMBL4615856	0.87	MCL1 (1.00)	MCL1KDM4EALDH1A1GPR35TTR
	SCHEMBL4655120	0.83	MCL1 (0.71)	MCL1KDM4EALDH1A1GPR35MEN1
	SCHEMBL11095441	0.83	MCL1 (0.70)	MCL1KDM4EALDH1A1TTRKMT2A
	SCHEMBL4738325	0.81	MCL1 (0.69)	MCL1KDM4EALDH1A1GPR35TTR
	SCHEMBL20893367	0.80	MCL1 (0.67)	MCL1KDM4EALDH1A1MEN1KMT2A
	SCHEMBL4763051	0.80	MCL1 (0.67)	MCL1KDM4EALDH1A1GPR35HPGD
	SCHEMBL16684635	0.80	MCL1 (0.67)	MCL1KDM4EALDH1A1GPR35KCNH2
	SCHEMBL10652526	0.80	MCL1 (0.67)	MCL1KDM4EALDH1A1GPR35MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.