Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099277 | 0.88 | MCL1 (0.70) | MCL1KCNH2ALDH1A1KDM4EKMT2A | |
| SCHEMBL1385653 | 0.83 | MCL1 (1.00) | MCL1KCNH2GAAALDH1A1KDM4E | |
| SCHEMBL20893367 | 0.77 | MCL1 (0.67) | MCL1KCNH2ALDH1A1KDM4EKMT2A | |
| SCHEMBL11095152 | 0.75 | PKM (0.64) | MCL1KCNH2GAAKDM4EKMT2A | |
| SCHEMBL719607 | 0.74 | MCL1 (0.63) | MCL1KCNH2ALDH1A1KDM4EKMT2A | |
| SCHEMBL11100621 | 0.74 | RAB9A (0.55) | MCL1GAAALDH1A1KDM4EKMT2A | |
| SCHEMBL6329907 | 0.73 | MCL1 (0.80) | MCL1KCNH2ALDH1A1KDM4EKMT2A | |
| SCHEMBL3498475 | 0.72 | MCL1 (0.78) | MCL1KCNH2GAAALDH1A1KDM4E | |
| SCHEMBL3500950 | 0.72 | MCL1 (0.60) | MCL1KCNH2ALDH1A1KDM4EKMT2A | |
| SCHEMBL8286023 | 0.71 | MCL1 (0.59) | MCL1GAAALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045473-B1 | A PHARMACEUTICAL COMPOSITION CONTAINING A BENZOFURAN-CARBOXAMIDE DERIVATIVE AS THE ACTIVE INGREDIENT | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1984-05-02 | — | — | EP | claimed |
| US-4353923-A | MUSCLE RELAXANTS, ANTIINFLAMMATORY, ANALGESIC | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1982-10-12 | — | — | US | claimed |
| EP-0045473-A1 | A pharmaceutical composition containing a benzofuran-carboxamide derivative as the active ingredient | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1982-02-10 | — | — | EP | claimed |