Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.49 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596069 | 0.80 | HSD17B10 (0.67) | HSD17B10HPGDCYP2C19CYP1A2CYP2D6 | |
| SCHEMBL25710684 | 0.79 | HSD17B10 (0.65) | HSD17B10HPGDCYP2C19CYP1A2CYP2D6 | |
| SCHEMBL15505858 | 0.75 | HSD17B10 (0.60) | HSD17B10HPGDCYP2C19CYP1A2CYP2D6 | |
| SCHEMBL2328498 | 0.75 | HSD17B10 (0.59) | HSD17B10HPGDCYP2C19CYP1A2CYP2D6 | |
| SCHEMBL2220947 | 0.75 | HSD17B10 (0.59) | HSD17B10HPGDCYP2C19CYP1A2CYP2D6 | |
| SCHEMBL22473836 | 0.75 | HSD17B10 (0.59) | HSD17B10HPGDCYP2C19CYP1A2CYP2D6 | |
| SCHEMBL7304753 | 0.75 | HSD17B10 (0.59) | HSD17B10HPGDCYP2C19CYP1A2CYP2D6 | |
| SCHEMBL2355481 | 0.75 | CYP1A2 (0.59) | HSD17B10HPGDCYP2C19CYP1A2CYP2D6 | |
| SCHEMBL3389391 | 0.74 | HSD17B10 (0.59) | HSD17B10HPGDCYP2C19CYP1A2CYP2D6 | |
| SCHEMBL8384856 | 0.74 | HSD17B10 (0.59) | HSD17B10HPGDCYP2C19CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | THE BURNHAM INSTITUTE (US) | 2009-05-07 | — | — | US | disclosed |
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | THE BURNHAM INSTITUTE (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | BCL2, BAX, BAD | HSD17B10 2065/4885HPGD 2147/4885CYP2C19 4858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.