Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22473836 | 0.88 | HSD17B10 (0.59) | HSD17B10CYP1A2CYP2D6CYP2C9HPGD | |
| SCHEMBL5596451 | 0.84 | HSD17B10 (0.56) | HSD17B10CYP1A2CYP2D6CYP2C9HPGD | |
| SCHEMBL8384856 | 0.82 | HSD17B10 (0.59) | HSD17B10CYP1A2CYP2D6CYP2C9HPGD | |
| SCHEMBL20340743 | 0.81 | CYP1A2 (0.53) | HSD17B10CYP1A2CYP2D6CYP2C9HPGD | |
| SCHEMBL17722824 | 0.81 | CYP1A2 (0.53) | HSD17B10CYP1A2CYP2D6CYP2C9HPGD | |
| SCHEMBL23861465 | 0.80 | CYP1A2 (0.51) | HSD17B10CYP1A2CYP2D6CYP2C9HPGD | |
| SCHEMBL17899124 | 0.80 | HPGD (0.56) | HSD17B10CYP1A2CYP2D6CYP2C9HPGD | |
| SCHEMBL4630970 | 0.79 | HSD17B10 (0.44) | HSD17B10CYP1A2CYP2D6CYP2C9HPGD | |
| SCHEMBL7304753 | 0.79 | HSD17B10 (0.59) | HSD17B10CYP1A2CYP2D6CYP2C9HPGD | |
| SCHEMBL1906196 | 0.78 | HSD17B10 (0.48) | HSD17B10CYP1A2CYP2D6CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110177454-A1 | RESIST MATERIAL AND PATTERN FORMATION METHOD USING THE RESIST MATERIAL | PANASONIC CORPORATION (JP) | 2011-07-21 | — | — | US | claimed |
| US-12030853-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030853-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2024-07-09 | — | — | US | disclosed |
| US-20230322788-A1 | IMIDAZOTRIAZINE AND PYRROLOPYRIMIDINE DERIVATIVES AS KRAS G12C INHIBITORS | BEONE MEDICINES I GMBH (CH) | 2023-10-12 | — | — | US | disclosed |
| US-20230322788-A1 | IMIDAZOTRIAZINE AND PYRROLOPYRIMIDINE DERIVATIVES AS KRAS G12C INHIBITORS | BEONE MEDICINES I GMBH (CH) | 2023-10-12 | — | — | US | disclosed |
| CN-112088198-B | Treatment agent for 6-valent chromium, method for treating pollutant containing 6-valent chromium, and method for treating bone ash containing 6-valent chromium | 西铁城时计株式会社 | 2023-10-03 | — | — | CN | disclosed |
| US-20210171461-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION | 2021-06-10 | — | — | US | disclosed |
| US-9895363-B2 | Methods for modulating function of proliferating cell nuclear antigen (PCNA) and treating cancer with PCNA-targeting compounds | UNIVERSITY OF CINCINNATI (US) | 2018-02-20 | — | — | US | disclosed |
| US-9895363-B2 | Methods for modulating function of proliferating cell nuclear antigen (PCNA) and treating cancer with PCNA-targeting compounds | UNIVERSITY OF CINCINNATI (US) | 2018-02-20 | — | — | US | disclosed |
| US-9884841-B2 | Small molecule inhibitors of Mcl-1 and uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-02-06 | — | — | US | disclosed |
| EP-0418064-B1 | Naphthalene and tetrahydronaphthalene gem-diphosphonate derivatives | SYMPHAR SA (CH) | 1994-12-14 | — | — | EP | disclosed |
| EP-0418064-A2 | Naphthalene and tetrahydronaphthalene gem-diphosphonate derivatives | SYMPHAR S.A. (CH) | 1991-03-20 | — | — | EP | disclosed |
| EP-0412851-A2 | Photosensitive member and multi-color image forming method | CANON KABUSHIKI KAISHA (JP) | 1991-02-13 | — | — | EP | disclosed |
| US-4546180-A | Process for preparing phosphite-isocyanurates oligomers | BORG-WARNER CHEMICALS, INC. (US) | 1985-10-08 | — | — | US | disclosed |
| EP-0074090-B1 | POLYMER STABILIZERS | BORG-WARNER CHEMICALS INC. (US) | 1985-09-04 | — | — | EP | disclosed |
| US-4460681-A | COLOR FORMING LAYERS, AND SOLVENT SOLUBLE BARRIE LAYERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0074090-A2 | Polymer stabilizers | BORG-WARNER CHEMICALS INC. (US) | 1983-03-16 | — | — | EP | disclosed |
| US-4376857-A | HEAT STABILIZERS FOR POLYMERS | BORG-WARNER CORPORATION (US) | 1983-03-15 | — | — | US | disclosed |
| US-4323714-A | Alkylation of hydroxy-substituted aromatic compounds | UOP INC. (US) | 1982-04-06 | — | — | US | disclosed |
| US-4210414-A | DISAZO AND NAPHTHOL DYES | BASF AKTIENGESELLSCHAFT (DE) | 1980-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322788-A1 | IMIDAZOTRIAZINE AND PYRROLOPYRIMIDINE DERIVATIVES AS KRAS G12C INHIBITORS | KRAS, NRAS, HRAS | HSD17B10 4594/4885CYP1A2 3955/4885CYP2D6 3502/4885 |
| US-12030853-B2 | MASP-2 inhibitors and methods of use | MASP2, METAP2, SPINT2 | HSD17B10 3100/4885CYP1A2 4271/4885CYP2D6 4456/4885 |
| US-20210171461-A1 | MASP-2 INHIBITORS AND METHODS OF USE | MASP2, METAP2, SPINT2 | HSD17B10 3100/4885CYP1A2 4271/4885CYP2D6 4456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.