SCHEMBL13857068

SCHEMBL13857068

C[Si](C)(Cl)CC[SiH3]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21811705 0.80
SCHEMBL149083 0.76 ALDH1A1 (0.46)
SCHEMBL706918 0.69 ALDH1A1 (0.39)
SCHEMBL5162971 0.69
SCHEMBL703423 0.69 ALDH1A1 (0.39)
SCHEMBL25216370 0.67 ALDH1A1 (0.36)
SCHEMBL8169552 0.67 ALDH1A1 (0.36)
SCHEMBL8166662 0.67 ALDH1A1 (0.36)
SCHEMBL8158855 0.67 ALDH1A1 (0.36)
SCHEMBL175548 0.67 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138111-A1 DE NOVO SYNTHESIZED GENE LIBRARIES Twist Bioscience Corporation (US) 2026-05-21 US disclosed
US-12569822-B2 De novo synthesized gene libraries Twist Bioscience Corporation (US) 2026-03-10 US disclosed
US-11697668-B2 Methods and devices for de novo oligonucleic acid assembly Twist Bioscience Corporation 2023-07-11 US disclosed
US-20230086062-A1 DE NOVO SYNTHESIZED GENE LIBRARIES Twist Bioscience Corporation 2023-03-23 US disclosed
US-20200299322-A1 METHODS AND DEVICES FOR DE NOVO OLIGONUCLEIC ACID ASSEMBLY Twist Bioscience Corporation 2020-09-24 US disclosed
US-8436103-B2 Star polymer and method of producing the same NIPPON SODA CO., LTD. (JP) 2013-05-07 US disclosed
US-20090118436-A1 Star Polymer and Method of Producing the Same NIPPON SODA CO., LTD. (JP) 2009-05-07 US disclosed