SCHEMBL149083

SCHEMBL149083

C[Si](C)(Cl)CC[Si](C)(C)Cl

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1554827 0.88 ALDH1A1 (0.36) ALDH1A1
SCHEMBL5032296 0.88 ALDH1A1 (0.36) ALDH1A1
SCHEMBL16461476 0.88 ALDH1A1 (0.36) ALDH1A1
SCHEMBL5032230 0.88 ALDH1A1 (0.36) ALDH1A1
SCHEMBL13377793 0.88 ALDH1A1 (0.36) ALDH1A1
SCHEMBL25216370 0.88 ALDH1A1 (0.36) ALDH1A1
SCHEMBL703423 0.82 ALDH1A1 (0.39) ALDH1A1
SCHEMBL706918 0.82 ALDH1A1 (0.39) ALDH1A1
SCHEMBL28966202 0.79
SCHEMBL8158855 0.79 ALDH1A1 (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583879-B2 Method for synthesizing C-nucleoside compound SICHUAN UNIVERSITY (CN) 2026-03-24 US claimed
CN-120116294-A Flame-retardant composite wood board and preparation method thereof 佛山和邦盛世家居有限公司 2025-06-10 CN claimed
EP-4323362-B1 METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES GILEAD SCIENCES INC (US) 2025-05-07 EP claimed
CN-117126199-B Fluororad West-Wei synthesis method 江西师范大学 2024-12-06 CN claimed
CN-118994170-A Process for preparing 1' -cyanonucleosides 吉利德科学公司 2024-11-22 CN claimed
CN-118588366-A PVC cable and preparation method thereof 广东百冠技术开发有限公司 2024-09-03 CN claimed
US-20240239830-A1 METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) 2024-07-18 US claimed
US-12012431-B2 Methods of preparing 1′-cyano nucleosides GILEAD SCIENCES, INC. (US) 2024-06-18 US claimed
CN-113637041-B Preparation method of ribonucleoside 上海科胜药物研发有限公司 2024-02-27 CN claimed
EP-4323362-A1 METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES GILEAD SCIENCES, INC. (US) 2024-02-21 EP claimed
EP-0856002-B1 PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS UPJOHN CO (US) 2001-10-24 EP claimed
US-5968962-A ANTIMICROBIAL AGENTS; EFFECTIVE AGAINST GRAMPOSITIVE BACTERIA PHARMACIA & UPJOHN COMPANY (US) 1999-10-19 US claimed
EP-0511568-B1 Polyorganosilazanes, process for their preparation and a process for making ceramic material BAYER AG (DE) 1995-08-02 EP claimed
US-5250648-A Preparation of organic silizane polymers and ceramic materials therefrom BAYER AKTIENGESELLSCHAFT (DE) 1993-10-05 US claimed
US-5230976-A Polymeric arylamine silane compounds and imaging members incorporating same XEROX CORPORATION (US) 1993-07-27 US claimed
EP-0511568-A1 Polyorganosilazanes, process for their preparation and a process for making ceramic material BAYER AG (DE) 1992-11-04 EP claimed
US-4869854-A Process for manufacturing organic silazane polymers and ceramics therefrom SHIN-ETSU CHEMICAL CO., LTD. (JP) 1989-09-26 US claimed
US-4847345-A Process for manufacturing organic silazane polymers and ceramics therefrom SHIN-ETSU CHEMICAL CO., LTD. (JP) 1989-07-11 US claimed
US-4339562-A High-molecular crystalline polymer with alternating dimethylene and methyl-substituted disilene units in the main chain and method for preparing same GUSELNIKOV LEONID E 1982-07-13 US claimed
US-4328350-A 1,1,2,2-Tetramethyl-1,2-disilacyclobutane and method for preparing same GUSELNIKOV LEONID E 1982-05-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12012431-B2 Methods of preparing 1′-cyano nucleosides PNP, TYMP, RNGTT ALDH1A1 629/4885
US-12583879-B2 Method for synthesizing C-nucleoside compound MTAP, NSUN2, BCDIN3D ALDH1A1 2793/4885
US-20240239830-A1 METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES NCL, DUT, POLN ALDH1A1 4201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.