SCHEMBL13857469

SCHEMBL13857469

COCCOCCSC[C@H](NC(=O)OCCOC)C(=O)NCC(=O)NC1C(O)CC(C)(C(=O)O)OC1[C@H](O)[C@H](O)CO

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CD22 P20273 15/20 0.36
▸ NANP Q8TBE9 1/20 0.33
▸ MAG P20916 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14454530 0.91 NANP (0.43) CD22NANP
SCHEMBL12341474 0.89 CD22 (0.37) CD22
SCHEMBL12341465 0.88 CD22 (0.35) CD22NANPMAG
SCHEMBL12341461 0.88 CD22 (0.39) CD22NANPMAG
SCHEMBL13931893 0.87 NANP (0.39) CD22NANP
SCHEMBL13948848 0.85 CD22 (0.36) CD22
SCHEMBL13402334 0.85 CD22 (0.38) CD22NANPMAG
SCHEMBL13948845 0.85 CD22 (0.34) CD22NANPMAG
SCHEMBL10260947 0.83 CD22 (0.35) CD22MAG
SCHEMBL17083472 0.82 CD22 (0.34) CD22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9187546-B2 Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants NOVO NORDISK A/S (DK) 2015-11-17 — — US disclosed
US-20090124544-A1 COMPOSITIONS AND METHODS FOR THE PREPARATION OF PROTEASE RESISTANT HUMAN GROWTH HORMONE GLYCOSYLATION MUTANTS NEOSE TECHNOLOGIES ,INC. A DELAWARE CORPORATION 2009-05-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090124544-A1 COMPOSITIONS AND METHODS FOR THE PREPARATION OF PROTEASE RESISTANT HUMAN GROWTH HORMONE GLYCOSYLATION MUTANTS GHITM, PTMS, GHRHR CD22 2233/4885NANP 386/4885MAG 1324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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