SCHEMBL14454530

SCHEMBL14454530

COCCOCCSC[C@H](NC(=O)OCCOC)C(=O)NCC(=O)NC1C(O)CC(OC)(C(=O)O)OC1[C@H](O)[C@H](O)CO

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ NANP Q8TBE9 2/20 0.43
▸ CD22 P20273 15/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12341461 0.93 CD22 (0.39) NANPCD22
SCHEMBL13857469 0.91 CD22 (0.36) NANPCD22
SCHEMBL13402334 0.90 CD22 (0.38) NANPCD22
SCHEMBL12341474 0.88 CD22 (0.37) CD22
SCHEMBL12341465 0.87 CD22 (0.35) NANPCD22
SCHEMBL15677307 0.87 NANP (0.51) NANPCD22
SCHEMBL13948848 0.85 CD22 (0.36) CD22
SCHEMBL12341459 0.85 NANP (0.39) NANPCD22
SCHEMBL13948845 0.84 CD22 (0.34) NANPCD22
SCHEMBL10260947 0.83 CD22 (0.35) CD22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070154992-A1 Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants NEOSE TECHNOLOGIES, INC. (US) 2007-07-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070154992-A1 Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants GHITM, PTMS, GHRHR NANP 386/4885CD22 2233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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