Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | GLA | P06280 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16659332 | 0.86 | KDM4E (0.70) | HDAC1ALDH1A1KDM4EGAALMNA | |
| SCHEMBL16659334 | 0.86 | KDM4E (0.70) | HDAC1ALDH1A1KDM4EGAALMNA | |
| SCHEMBL16659333 | 0.86 | KDM4E (0.70) | HDAC1ALDH1A1KDM4EGAALMNA | |
| SCHEMBL16198921 | 0.86 | KDM4E (0.70) | HDAC1ALDH1A1KDM4EGAALMNA | |
| SCHEMBL5903723 | 0.85 | HDAC1 (1.00) | HDAC1ALDH1A1KDM4EGAALMNA | |
| SCHEMBL8328245 | 0.82 | HDAC1 (0.76) | HDAC1ALDH1A1KDM4EGAALMNA | |
| SCHEMBL8572753 | 0.81 | ALDH1A1 (0.96) | HDAC1ALDH1A1KDM4EGAALMNA | |
| SCHEMBL20181377 | 0.81 | ALDH1A1 (0.96) | HDAC1ALDH1A1KDM4EGAALMNA | |
| SCHEMBL498680 | 0.81 | HDAC1 (0.64) | HDAC1ALDH1A1KDM4EGAALMNA | |
| SCHEMBL4319368 | 0.80 | ALDH1A1 (1.00) | HDAC1ALDH1A1KDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137789-A1 | Oligonucleotide Probes | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137789-A1 | Oligonucleotide Probes | NCL, RNGTT, NSUN3 | HDAC1 2126/4885ALDH1A1 2227/4885KDM4E 4808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.