Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19834905 | 0.76 | ALDH1A1 (0.35) | ALDH1A1CFTRGOPC | |
| SCHEMBL7823616 | 0.68 | ALDH1A1 (0.32) | ALDH1A1CFTRGOPCL3MBTL1 | |
| SCHEMBL3333377 | 0.65 | ALDH1A1 (0.38) | ALDH1A1CFTRGOPCL3MBTL1 | |
| SCHEMBL11165595 | 0.65 | CYP11B1 (0.37) | ALDH1A1CFTRGOPCLMNA | |
| SCHEMBL26118035 | 0.63 | ALDH1A1 (0.47) | ALDH1A1LMNA | |
| SCHEMBL1097512 | 0.62 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL10784242 | 0.62 | — | — | |
| SCHEMBL22264953 | 0.62 | — | — | |
| SCHEMBL20722299 | 0.59 | ALDH1A1 (0.42) | ALDH1A1CFTRGOPCL3MBTL1LMNA | |
| Biphenyl SCHEMBL27765460 | 0.58 | ALDH1A1 (0.69) | ALDH1A1LMNATSHRALOX12ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012158413-A2 | PYRROLIDINYL UREA AND PYRROLIDINYL THIOUREA COMPOUNDS AS TRKA KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2012-11-22 | — | — | WO | disclosed |