SCHEMBL7823616

SCHEMBL7823616

C[C]1C=CC=C(c2ccccc2)C1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
SIGMAR1 Q99720 1/20 0.31
CFTR P13569 1/20 0.31
GOPC Q9HD26 1/20 0.31
HTR2C P28335 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19834905 0.78 ALDH1A1 (0.35) ALDH1A1SIGMAR1CFTRGOPCHTR2C
SCHEMBL28664458 0.77 ALDH1A1 (0.33) ALDH1A1SIGMAR1CFTRGOPCHTR2C
SCHEMBL23501862 0.76 NPC1 (0.34) ALDH1A1NPC1RAB9A
SCHEMBL28199530 0.75 CFTR (0.40) ALDH1A1SIGMAR1CFTRGOPCNPC1
SCHEMBL7821424 0.75 ALDH1A1 (0.32) ALDH1A1SIGMAR1CFTRGOPCHTR2C
SCHEMBL27546185 0.75 ALDH1A1 (0.40) ALDH1A1SIGMAR1CFTRGOPCHTR2C
SCHEMBL7820798 0.75 HSD11B1 (0.32)
SCHEMBL7825478 0.72 ALDH1A1 (0.38) ALDH1A1CFTRGOPCL3MBTL1NPC1
SCHEMBL3982745 0.71 ALDH1A1 (0.47) ALDH1A1SIGMAR1CFTRGOPCHTR2C
SCHEMBL21495135 0.71 TAAR1 (0.42) ALDH1A1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113207294-B Polymer resin composition, and polymer film and resin laminate using same 株式会社LG化学 2023-10-20 CN disclosed
CN-113207294-A Polymer resin composition, and polymer film and resin laminate using same 株式会社LG化学 2021-08-03 CN disclosed
WO-2021118143-A1 POLYMER RESIN COMPOSITION, AND POLYMER FILM AND RESIN LAMINATE USING SAME 주식회사 엘지화학 2021-06-17 WO disclosed
EP-1144381-A2 SUBSTITUTED BENZO[DE]ISOQUINOLINE-1,3-DIONES MERCK PATENT GmbH (DE) 2001-10-17 EP disclosed
EP-1133475-A1 SUBSTITUTED BENZO DE]ISOQUINOLINE-1,3-DIONES MERCK PATENT GmbH (DE) 2001-09-19 EP disclosed
WO-2000032577-A2 SUBSTITUTED BENZO[DE]ISOQUINOLINE-1,3-DIONES MERCK PATENT GMBH (DE) 2000-06-08 WO disclosed
WO-2000031039-A1 SUBSTITUTED BENZO[DE]ISOQUINOLINE-1,3-DIONES MERCK PATENT GMBH (DE) 2000-06-02 WO disclosed