Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13858832 | 0.71 | GSK3B (0.36) | TNKS2GSK3B | |
| SCHEMBL9535536 | 0.66 | KDM4E (0.33) | TNKS2GSK3B | |
| SCHEMBL22199012 | 0.64 | TNKS2 (0.37) | TNKS2GSK3B | |
| SCHEMBL19142929 | 0.63 | GSK3B (0.40) | TNKS2GSK3B | |
| SCHEMBL24735437 | 0.60 | GSK3B (0.33) | TNKS2GSK3B | |
| SCHEMBL29362460 | 0.60 | CYP1A2 (0.31) | — | |
| SCHEMBL870400 | 0.60 | CYP1A2 (0.31) | — | |
| SCHEMBL6616782 | 0.58 | CYP1A2 (0.30) | — | |
| SCHEMBL29700709 | 0.58 | CYP1A2 (0.30) | — | |
| SCHEMBL9004905 | 0.57 | TRPA1 (0.37) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012158197-A2 | COMPOUNDS USEFUL AS AKT/PKB MODULATORS AND USES THEREOF | LYNDOR BIOSCIENCES L.L.C. (US) | 2012-11-22 | — | — | WO | claimed |
| WO-2012158197-A2 | COMPOUNDS USEFUL AS AKT/PKB MODULATORS AND USES THEREOF | LYNDOR BIOSCIENCES L.L.C. (US) | 2012-11-22 | — | — | WO | disclosed |