Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13720474 | 0.88 | KDM4E (0.47) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL13721693 | 0.84 | KDM4E (0.46) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL13720169 | 0.83 | ALDH1A1 (0.48) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL13858646 | 0.83 | ALDH1A1 (0.50) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL13721052 | 0.82 | KDM4E (0.47) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL13721076 | 0.80 | KMT2A (0.49) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL13721548 | 0.79 | KDM4E (0.51) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL30795062 | 0.79 | ADRA1A (0.51) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL1790428 | 0.79 | ADRA1A (0.51) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL13720538 | 0.79 | KDM4E (0.48) | KDM4EHPGDALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012158399-A1 | CONDENSED 2 - CARBAMOYLPYRIDAZINONES AS POTASSIUM CHANNEL MODULATORS | ABBOTT LABORATORIES (US) | 2012-11-22 | — | — | WO | disclosed |