Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 14/20 | 0.72 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.72 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.72 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.72 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.72 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.72 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.72 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.72 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.72 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.72 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520815 | 1.00 | HDAC1 (0.72) | HDAC1HDAC4HDAC8HDAC3HDAC7 | |
| SCHEMBL1520819 | 1.00 | HDAC1 (0.72) | HDAC1HDAC4HDAC8HDAC3HDAC7 | |
| SCHEMBL12395351 | 0.86 | HDAC1 (0.71) | HDAC1HDAC4HDAC8HDAC3HDAC7 | |
| SCHEMBL13465162 | 0.85 | HDAC1 (0.70) | HDAC1HDAC4HDAC8HDAC3HDAC7 | |
| SCHEMBL1521160 | 0.85 | HDAC1 (0.70) | HDAC1HDAC4HDAC8HDAC3HDAC7 | |
| SCHEMBL1521164 | 0.85 | HDAC1 (0.70) | HDAC1HDAC4HDAC8HDAC3HDAC7 | |
| Trichostatin SCHEMBL16380793 | 0.84 | HDAC1 (1.00) | HDAC1HDAC4HDAC8HDAC3HDAC7 | |
| SCHEMBL1521161 | 0.84 | HDAC1 (0.69) | HDAC1HDAC4HDAC8HDAC3HDAC7 | |
| Trichostatin SCHEMBL675951 | 0.84 | HDAC1 (1.00) | HDAC1HDAC4HDAC8HDAC3HDAC7 | |
| Trichostatin SCHEMBL446806 | 0.84 | HDAC1 (1.00) | HDAC1HDAC4HDAC8HDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130064-A1 | DIFFERENTIATION OF STEM CELLS AND STABILIZATION OF PHENOTYPICAL PROPERTIES OF PRIMARY CELLS | VRIJE UNIVERSITEIT BRUSSEL (BE) | 2009-05-21 | — | — | US | disclosed |