Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10182557 | 0.82 | MAPT (0.45) | MAPTPOLBPKMELANEHSD17B10 | |
| SCHEMBL12673729 | 0.81 | CA1 (0.62) | MAPTELANELMNAMEN1KMT2A | |
| SCHEMBL13419229 | 0.81 | THRB (0.47) | MAPTPOLBPKMHSD17B10LMNA | |
| SCHEMBL8850878 | 0.81 | ELANE (0.64) | MAPTPOLBPKMELANEHSD17B10 | |
| SCHEMBL9760675 | 0.81 | ELANE (0.64) | MAPTPOLBPKMELANEHSD17B10 | |
| SCHEMBL9507144 | 0.79 | ELANE (0.62) | MAPTPOLBPKMELANEHSD17B10 | |
| SCHEMBL25316699 | 0.77 | ELANE (0.60) | MAPTPOLBPKMELANEHSD17B10 | |
| SCHEMBL4647885 | 0.77 | CA1 (0.67) | MAPTPOLBELANEHSD17B10LMNA | |
| SCHEMBL5864662 | 0.77 | ELANE (0.60) | MAPTPOLBPKMELANEHSD17B10 | |
| SCHEMBL14451127 | 0.77 | CA12 (0.57) | MAPTPKMLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534475-B2 | Liquid crystal compound comprising two condensed and substituted rings | FUJIFILM CORPORATION (JP) | 2009-05-19 | — | — | US | disclosed |
| US-20070176145-A1 | Liquid crystal compound comprising two condensed and substituted rings | FUJI PHOTO FILM CO., LTD. (JP) | 2007-08-02 | — | — | US | disclosed |