Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.64 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 8/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11956939 | 0.92 | METTL3 (0.56) | METTL3 | |
| SCHEMBL11957090 | 0.89 | METTL3 (0.50) | METTL3 | |
| SCHEMBL1046249 | 0.89 | METTL3 (0.81) | METTL3PLA2G4AEGFRGAATP53 | |
| SCHEMBL1046251 | 0.89 | METTL3 (0.81) | METTL3PLA2G4AEGFRGAATP53 | |
| SCHEMBL26076850 | 0.89 | METTL3 (0.80) | METTL3PLA2G4AEGFRGAACNR2 | |
| SCHEMBL3232336 | 0.88 | METTL3 (0.67) | METTL3PLA2G4AEGFRGAATP53 | |
| SCHEMBL25726695 | 0.88 | METTL3 (0.69) | METTL3PLA2G4AEGFRGAATP53 | |
| SCHEMBL11956108 | 0.84 | METTL3 (0.44) | METTL3TP53MAPT | |
| SCHEMBL12107653 | 0.83 | METTL3 (0.46) | METTL3EGFRCNR2TP53 | |
| SCHEMBL4371074 | 0.83 | METTL3 (0.74) | METTL3PLA2G4AEGFRGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531554-B2 | Useful as an anti-HIV agent that particularly shows an anti-HIV action based on an integrase inhibitory activity; for treatment or prophylaxis of AIDS; for example, 6-(2,3-dichlorobenzyl)-1-(2-hydroxyethyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | JAPAN TOBACCO INC. (JP) | 2009-05-12 | — | — | US | disclosed |