Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13862207 | 0.89 | METTL3 (0.64) | METTL3 | |
| SCHEMBL13862208 | 0.88 | METTL3 (0.48) | METTL3CFD | |
| SCHEMBL15082529 | 0.88 | METTL3 (0.65) | METTL3CFDTHRB | |
| SCHEMBL11948689 | 0.88 | METTL3 (0.64) | METTL3SLC22A12PKMCFDTHRB | |
| SCHEMBL11956939 | 0.88 | METTL3 (0.56) | METTL3PTPN1 | |
| SCHEMBL11956108 | 0.87 | METTL3 (0.44) | METTL3SLC22A12PTPN1CFD | |
| SCHEMBL11956954 | 0.86 | METTL3 (0.49) | METTL3SLC22A12PKMCFDTHRB | |
| SCHEMBL12413342 | 0.82 | METTL3 (0.42) | METTL3PTPN1CFDTHRB | |
| SCHEMBL12107653 | 0.81 | METTL3 (0.46) | METTL3PTPN1CFD | |
| SCHEMBL13771406 | 0.80 | METTL3 (0.40) | METTL3PTPN1CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232401-B2 | Useful as an anti-HIV agent that particularly shows an anti-HIV action based on an integrase inhibitory activity; for treatment or prophylaxis of AIDS; for example, 6-(2,3-dichlorobenzyl)-1-(2-hydroxyethyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | JAPAN TOBACCO INC. (JP) | 2012-07-31 | — | — | US | disclosed |